If your results are negative for both tests (anti-CCP and RA), it is likely that the arthritis is due to a cause other than rheumatoid arthritis.Changes various names of the novel coronavirus to 'CCP virus'. Negative anti-CCP test + negative RA test If you have negative results in the anti-CCP test but positive results in the RA test, the symptoms and clinical signs will determine the diagnosis for the disease. Negative anti-CCP test + positive RA test If you have suggestive signs of rheumatoid arthritis and positive results in the anti-CCP test but negative results in the RA test, or if you are symptomatic with weak results in both tests, it is likely that you are in the early phase of the disease or that it will develop in the future. Slightly positive anti-CCP test + slightly positive RA test Positive anti-CCP test + negative RA test If you have signs or symptoms of arthritis, positive results in both the anti-CCP and RA tests are highly predictive of rheumatoid arthritis and you may develop a more progressive and severe form.
Positive anti-CCP test + positive RA test: The detection of anti-CCP antibodies confirms the presence of rheumatoid arthritis, establishes a prognosis for the progression of the disease and helps determine the best possible treatment. There are several dozen forms of arthritis (joint inflammation): in addition to the autoimmune varieties such as rheumatoid arthritis or lupus, there are cases of arthritis due to aging (“normal” wear and tear), gout, and fractures or infections (viruses, bacteria or fungi). The immune system’s production of antibodies against its own cyclic citrullinated peptides is the cause of rheumatoid arthritis.
Several types of arthritis, lupus, pernicious anemia, juvenile diabetes and some thyroid disorders are autoimmune in origin. The production of antibodies against its own tissues is the cause of a large number of “autoimmune” diseases. Often, the immune system goes awry and confuses some of its own tissues as foreign. The immune system is responsible for defending the body against attacks from foreign cells and organisms: bacteria, viruses, parasites and transplanted cells. These products fulfill several cellular functions. This test is used to help diagnose and prognosticate rheumatoid arthritis and differentiate it from other types of arthritis.ĬCPs (cyclic citrullinated peptides) come from the maturation of proteins in the body.
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